Press release

Septodont reinforces its footprint in Endodontics with the launch of GenENDO

Published September 18, 2025

Septodont, is proud to announce the launch of GenENDO1, a range of endodontic files designed to support easy and successful shaping of the root canal.



This launch stems from a strategic partnership with Micro-Mega, through which Septodont will exclusively distribute the GenENDO range. This collaboration brings together Micro-Mega’s expertise in endodontic instrumentation and Septodont’s global reach in dental innovation.





Stéphane ClaudeDeputy General Manager at Coltene Micro-Mega

“ The strategic alignment between Micro-Mega and Septodont marks a significant milestone, combining complementary expertise to deliver enhanced value to our clients,” said Stéphane Claude, Deputy General Manager at Coltene Micro-Mega. “This partnership leverages Micro-Mega’s deep industry knowledge and Septodont’s innovative capabilities, fostering a collaborative environment that drives growth, innovation, and long-term success. ”





This collaboration reinforces Septodont’s commitment to expanding its endodontic portfolio.

With GenENDO, the company introduces a short, efficient, and easy-to-use rotary file system that simplifies the shaping of root canals, making it more accessible to general practitioners and specialists alike.



The introduction of GenENDO builds on the success of BioRoot™ Flow2, a bioactive sealer that, in a recent clinical study, demonstrated a 91% clinical success rate after two years3.



Designed to simplify the obturation step, BioRoot™ Flow is recognized for its ease of use and reliable performance.





Nicolas RouziouxChief Marketing Officer at Septodont

“ At Septodont, innovation is part of our DNA, we’re committed to delivering solutions that empower dentists in their everyday practice,” said Nicolas Rouzioux, Chief Marketing Officer. “Our collaboration with Micro-Mega strengthens our footprint in endodontic treatment and complements our BioRoot™ range, reinforcing our dedication to excellence in dental care. ”





By offering solutions for both shaping and obturation, GenENDO and BioRoot™ Flow make endo easy and successful4 providing clinicians with a comprehensive approach to root canal treatment that supports long-term outcomes.





















References

1.GenENDO K-Files (A)/GenENDO Remover (B)/GenENDO Glider (B)/GenENDO Revo-S+ (B) are medical devices intended for use by dental professionals only, during non-surgical endodontic treatment. Manufactured by Micro-Mega, France. CE marked (CE 0459) Class I in accordance with Regulation (EU) 2017/745 (A) or Class IIa in accordance with MDD (B).

2.BioRoot™ Flow: is a medical device intended for permanent root canal filling material in combination with gutta-percha points in case of inflamed or necrotic pulp or following a retreatment procedure. Manufactured by Septodont, France. CE marked (CE 2797) Class III implantable. 

Both BioRoot Flow and GenENDO can be used together or separately in endodontic procedures.

3.Loose criteria evaluation (Clinicaltrials.gov). Strict criteria evaluation at 24 months post-treatment, the overall success rate was 86.6% in the BioRoot Flow group and 87.7% in the BioRoot™ RCS group (non-inferiority demonstrated; p = .0195) (Simon S and Al. Clinical efficacy of root canal treatment at 2 years using a new ready-to- use injectable calcium silicate-based sealer: A multicentric randomised controlled trial. Int Endod J. 2025;00:1–1).



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